Motor system neuromodulation and repair
 Society for Neuroscience | |
 United States, New York, New York | |
 Dec 30, 2024 | |
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Motor system neuromodulation and repair
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Job Details Postdoctoral positions are available to study corticospinal system plasticity and repair after spinal cord injury at the City University of New York School of Medicine in rats. Our-state-of-the-art laboratory is located at the Center for Discovery and Innovation on the City College of New York campus in northern Manhattan. A major focus of the lab's research program is the study of activity-dependent corticospinal axon growth and strengthening of corticospinal system connections (for a list of publications, see Martin Lab website:http://martinlab.ccny.cuny.edu). We leverage the knowledge gained to develop neuromodulation strategies for neural repair after injury. The current projects focus on a novel combined biomaterial-neuromodulation strategy to repair the spinal injury site and to promote functional connectivity. Other projects in the lab include promoting motor learning using different neuromodulation strategies, in collaboration with the Lucas Parra laboratory in Biomedical Engineering at The City College of NY. The present position is funded through grants from the NIH and the NYS Spinal Cord Injury Research Board. We use different neuromodulation approaches (several electrical stimulation protocols, optogenetics, DREADDs) to promote axon outgrowth and strengthen corticospinal system connections in healthy animals and after cervical contusion SCI. Outcomes are assessed using CNS and muscle electrophysiology; anatomical changes, including use of tissue clearing methods; and behavioral techniques (reaching, locomotion, reflex testing). It is particularly important that applicants have adequate experience conducting animal surgeries and in vivoprocedures. Applicants with training in Matlab (or equivalent) programming and animal behavioral approachesare encouraged to apply. Email CV and the names and contact information of three references to John H. Martin, Ph.D. (jmartin@med.cuny.edu). Martin lab website: http://martinlab.ccny.cuny.edu The Research Foundation of the City University of New York is an Equal Opportunity/Affirmative Action/American with Disabilities Act/E-Verify Employer Company The Martin laboratory studies how the nervous system controls limb movement, such as walking and reaching, from the dual perspectives of brain development and recovery of motor function after brain or spinal cord injury. Our studies focus on the corticospinal motor system and on the spinal motor circuits that are the targets of the corticospinal system. We are interested in elucidating the mechanisms by which the specificity of these connections are established during development and in devising ways to reestablish this specificity after injury. We use a diversity of animal models to study the question of corticospinal system development and repair. An important focus of the lab is to translate what we learn in the animal into therapies for humans with mobility impairments. Research in the lab is supported by grants from the NIH, NYS Department of Health, and private foundations.
The laboratory, which is part of the City University of New York School of Medicine, is located at the City College of NY South Campus in northern Manhattan, in the Center for Discovery and Innovation. The South Campus is also where the CUNY Advanced Science Research Center is located. The CCNY Center for Discovery and Innovation and the CUNY Advanced Science Research Center together comprise CUNY's newest premier science research facility. Please see the laboratory website for updates : http://martinlab.ccny.cuny.edu/ | |