New 
Scientist
 Spectraforce Technologies | |
 United States, Massachusetts, Worcester | |
 Jan 14, 2025 | |
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Job Title: Scientist II
Location: Worcester, Massachusetts 01604 Duration: 12 Months (Possible extension) The Biotherapeutics and Genetic Medicine Group at Company Bioresearch Center in Worcester, MA is seeking a highly motivated scientist for rAAV analytical characterization for gene therapy in a newly established rAAV Research and Production team. The candidate will work collaboratively with our therapeutic area teams to advance Company's rAAV pipeline. The ideal candidate will have biotechnology experience in rAAV Process and Analytical Development. He/she will be responsible for assisting with the development and execution of analytical methods to support preclinical studies. This position requires a versatile individual, who can work in development and analytical activities to advance pipeline. Key Responsibilities Include: * Assist in the development and application of molecular and cell-based assays (e.g., ELISA, SDS-PAGE, WB, WES, Endotoxin assay) * Maintain and culture cells or assist in AAV production as needed * Analyze experimental data, generating plots and summarizing results and conclusions * Maintain a comprehensive Electronic Lab Notebook documenting experiments * Maintain a high level of productivity in the team with clear daily, detailed, and accurate documentation of experiments * Collaborate with team members to meet project goals, and advance novel vectors into pipeline * Author technical reports and protocols * Understand and enforce company culture, teamwork, safety, appropriate handling of materials in an BSL2 environment * Perform all activities in compliance with applicable regulations, Company's policies and guidelines * Bring a "can do" spirit to work and deliver on other responsibilities as assigned Qualifications Basic: * Bachelor's with 3-5 years of experience or Master's in Biology or related discipline * Experience in molecular assay development and optimization (e.g., ddPCR, WB, WES, SDS-PAGE) * Experience in rAAV production using mammalian cell platforms * Experience in cell culture work (e.g., maintenance, transfection, transduction) * Ability to work effectively in a highly collaborative and dynamic environment * Successful track record of working in high-growth and dynamic organizations * Excellent verbal and written communication skills * Evidence of "hands-on" experience and expertise * Organized and detail oriented with a passion to deliver quality results | |