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Associate Scientist, Biologics Lead Optimization

Neurocrine Biosciences
United States, California, San Diego
Jan 15, 2025
Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.

What We Do:

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine, and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visitneurocrine.com, and follow the company on LinkedIn, X (Formerly Twitter) and Facebook. (*in collaboration with AbbVie)

About the Role:

Assists with set up and execution of processes to express and purify antibodies and other protein therapeutic agents. Will also assist in carrying out biochemical and biophysical analyses to characterize the identity, purity and stability of novel therapeutics. Analyzes and presents data to lead scientists in an organized and timely manner. Coordinates closely with protein engineering and project teams. Performs work in collaboration with other members of the biologics lead optimization team as well as protein engineering teams. Makes detailed observations, analyzes data and interprets results with some supervision. Investigates, creates and develops new methods and technologies for project advancement. Obtains professional expertise through familiarity with scientific literature and educational tools. May participate in scientific conferences and contribute to scientific journals. This position will also support gene therapy research programs.

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Your Contributions (include, but are not limited to):
  • Performs experiments with some supervision in support of scientific activities and project goals involving antibody and protein production and characterization

  • Follows new methods and techniques and seeks out senior personnel for training and to discuss clarifications and explanations of methods and results

  • Generates complex biochemical and biophysical data sets following SOPs, and assists in data analysis

  • Assists in maintenance protein purification equipment and cleaning and stocking of equipment and rooms

  • Follows SOPs and organizes data for experiments conducted, and presents data to research team members

  • Complies with all SOPs, and safety and quality assurance standards at all times

  • May assist in research and support of gene therapy drug development

  • Other duties as assigned

Requirements:
  • BS/BA degree and some relevant experience preferred

  • Knowledge of basic chemical and biological principles

  • Ability to follow complex instructions to perform detailed experimental procedures

  • Understand and implement safe working practices in a laboratory environment

  • Able to execute experiments efficiently and suggest process improvements

  • Able to recognize patterns or inconsistencies in data results

  • Able to deduce meaningful results while conducting routine analyses or troubleshoot minor issues. Good knowledge of one scientific discipline

  • Developing knowledge of scientific principles, methods and techniques

  • Good knowledge and some experience working with discipline specific laboratory equipment/tools

  • Ability to work as part of a team

  • Good computer skills

  • Developing communications, problem-solving, analytical thinking, planning and organization skills

  • Detail oriented

  • Understands importance of meeting deadlines

Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.

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The hourly rate we reasonably expect to pay is $34.66-$48.98. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 15% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.
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