Senior Researcher, Biology

At Eisai, satisfying unmet medical needs and increasing the benefits healthcare provides to patients, their families, and caregivers is Eisai's human health care (hhc) mission. We're a growing pharmaceutical company that is breaking through in neurology and oncology, with a strong emphasis on research and development. Our history includes the development of many innovative medicines, notably the discovery of the world's most widely-used treatment for Alzheimer's disease. As we continue to expand, we are seeking highly-motivated individuals who want to work in a fast-paced environment and make a difference. If this is your profile, we want to hear from you.

General Summary:

The Eisai Center for Genetics Guided Dementia Discovery (G2D2) is an industry-unique drug discovery biotech with a diverse group of passionate, dedicated and collaborative scientists committed to helping eradicate Alzheimer's disease and other dementias. Recognizing the potential for human genetics, data sciences and precision chemistry to disrupt the drug discovery paradigm, Eisai established G2D2 to accelerate the discovery of innovative therapeutics. G2D2 is committed to accelerating drug discovery premised upon robust insights from human biology, and driving multi-disciplinary team-based progress towards addressing real unmet patient needs.

At G2D2, we focus not only on how such data help identify and validate therapeutic targets, but also to guide novel approaches to drug such targets and match them to the right patient at the right time. Our precision chemistry strategy - in the context of insights from human genetics - is uniquely positioned to deliver tailor-designed small molecule, anti-sense oligo-nucleotide, and other solutions for targeted therapeutics.

Our new cutting-edge 50,000-square-foot facility is strategically locatedin Cambridge, MA,to accelerate collaborations with leading research institutesin thisworld-class biotech hub. Our facility has been designed around a novel open-lab concept, enabling chemists, biologists, automation and other scientists to work together in a single common and integrated lab space. Our labs include state-of-the-art capabilities in medicinal and process chemistry, in-vitro and in-vivo biology, microscopy, chemical and structural biology, automation and screening, and several other discovery technologies and platforms.

You will join a highly interactive and collaborative team spanning a broad range of drug discovery capabilities. We highly value both internal and external collaborations, and you will become involved in flexible research models with a range of external scientific partners to accelerate delivery of innovative medicines. As an Eisai employee you will spend at least 1% of your working time with patients and families to ensure that the innovation you drive is based on an understanding of their real needs.

More information about G2D2 is provided here (http://eisai.mediaroom.com/2018-06-12-Eisai-Inc-to-Launch-Center-for-Genetics-Guided-Dementia-Discovery-in-Cambridge-Massachusetts) and here (https://us.eisai.com/research/g2d2), and about Eisai's Neurology strategy and pipeline are provided here (https://www.eisai.com/index.html).

We are seeking a Senior Researcher, Biology. This position identifies and validates molecular targets that play a key role in a particular disease process. The Sr. Researcher studies origin, relationship, development, anatomy, functions, and chemical processes of living organisms. This position also analyzes materials to determine their toxic or nontoxic properties, binding and efficacy. Isolates or purifies analyses, and identifies hormones, minerals, proteins, and/or cultures of microorganisms to determine their biological properties. The Sr. Researcher examines and conducts research on chemical aspects chemistry of cells and cell division. This role may also develop an assay which employs in-vitro and/or in-vivo biological and immunological systems. Additionally, this role may experiment with animals and tissue to determine the effect of new drug compound entities utilizing in-vivo, in-vitro and ex-vivo models on cells, tissues and whole animal systems.

Responsibilities:

• Conduct activities related to assigned research study(e.g. experiment design and execution; storage and cross-referencing of materials and samples; report processing, interpretation, and record-keeping of experimental results) as instructed
• Maintain and effectively use current laboratory equipment, chemicals and supplies; support the testing of standard procedures and assist in developing recommendations for improvement
• Optimize standardized/pre-described lab processes in assigned technology/study; contribute to exploration of new ideas
• Support planning of resources and monitoring, ordering, and stocking of research needs
• Periodically present results to team in project meetings

Qualifications:

• Bachelor's degree in relevant technical area with 2+ years of experience. Experience in R&D methods and processes in industry setting required;(OR)Master's degree with no prior industry experience but with academic research experience or industry internships may be considered
• An understanding of one or more of the following: molecular biology, biochemistry, microbiology, cell biology, biophysics, virology and/or immunology is required. The incumbent may also identify and produce small quantities of new drugs, pharmaceutical compounds and/or nutrients.

Eisai Salary Transparency Language:

Final pay determinations will depend on various factors including but not limited to experience level, education, knowledge, and skills.

Employees are eligible to participate in Company employee benefit programs. For additional information on Company employee benefits programs, visit https://us.eisai.com/careers-at-eisai/benefits.

Certain other benefits may be available for this position, please discuss any questions with your recruiter.

Eisai is an equal opportunity employer and as such, is committed in policy and in practice to recruit, hire, train, and promote in all job qualifications without regard to race, color, religion, gender, age, national origin, citizenship status, marital status, sexual orientation, gender identity, disability or veteran status. Similarly, considering the need for reasonable accommodations, Eisai prohibits discrimination against persons because of disability, including disabled veterans.

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