New

Senior Software Engineer, Instrument Software

10x Genomics Inc
United States, California, Pleasanton
6230 Stoneridge Mall Road (Show on map)
Jun 20, 2025
About the role 10x Genomics was founded to deliver powerful and reliable tools that fuel key scientific discoveries and drive exponential progress in our mastery of biology to advance human health. Our talented team has a distinguished record of creating innovative instruments, reagents, and software that analyze biological systems at a resolution that matches the complexity of biology. We are looking for a Senior Software Engineer to join our Instrument Software team. You have expert-level knowledge of creating advanced instrument control software & firmware with C, C++, Python and/or Rust. You can handle threading, multiprocessing and interfacing with low-level drivers, firmware & hardware with ease. You are a stickler for testing and thrive on creating a clean and maintainable codebase. You are a system level thinker who weighs how the design decision you make today will have an impact days, months, and even years down the line. You are the engineer that other engineers can count on; you are technically excellent, you attack every problem with enthusiasm, you care deeply about what it takes to build high quality software. You will be working closely with fluidics, electrical, mechanical, optical, and fellow embedded software engineers (and the occasional biologist) to design, implement, and deploy algorithms and tools that allow us to iterate on new designs quickly and confidently. You love distilling a problem to first principles to understand it from equations on paper to compiled code. Ideal candidates will be independent operators that enjoy working in a lab or on the manufacturing floor with physical components and have a deep understanding of real-time asynchronous systems. Applicants must love tinkering and have a true hacker mindset. What you will be doing Designing and developing embedded control software and firmware for cutting edge biological instrumentation platforms Working with mechanical and electrical engineers to inform design and develop appropriate control schemes and interfaces Contributing to the entire software lifecycle from requirements gathering to validation Writing well structured, testable, efficient and maintainable software Taking ownership of calibration and verification tools prototyped by other technical teams (e.g. Optical Engineering, Electrical Engineering) and turning it into robust, deployable software Collaborating with manufacturing teams on the factory floor to troubleshoot new failure modes and identify necessary process or software changes to prevent recurrence. Building simulation and observability tools that allow order of magnitude throughputs improvements Effectively communicating complex technical issues to stakeholders with a variety of technical depth Minimum requirements Bachelor's degree in computer science, engineering, math, or scientific discipline with 5 years experience; OR Master's degree with 3 years of experience in software development; OR PHD with 1 year of experience in software development Embedded/Firmware Development C or Modern C++ Python3 Linux Preferred skills and experience Confident usage of Python scientific and numerical computing and visualization packages (e.g. numpy, pandas, matplotlib) EE knowledge (Digital & Analog Design) and familiarity with laboratory test equipment (e.g. digital multimeter, oscilloscope, signal analyzer, etc.) Rapid software prototyping & validation with attention to detail and engineering diligence Strong analytical and problem-solving skills Strong verbal and written communication skills Formal approach to design & architecture of complex systems Exposure to ROS Familiarity with modeling and control of robotic systems (e.g. rigid body transforms, forward/inverse kinematics, motion planning) Familiarity with state estimation algorithms Grasp of the basics of machine vision and experience using toolkits like OpenCV and Scikit-Image. (e.g. SIFT, 2D phase correlation) Background in biology and DNA sequencing is not required. Interest in the field is. #LI-RT1 #LI-Onsite Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, and experience. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company's total compensation package. Pay Range $183,000 — $247,600 USD About 10x Genomics At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation,or any other characteristic protected by applicable law. 10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.