New 
Bioinformatics Specialist I
 Massachusetts General Hospital | |
 United States, Massachusetts, Boston | |
| 185 Cambridge Street (Show on map) | |
 May 11, 2026 | |
|
The Talkowski Laboratory in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) and the Broad Institute of MIT and Harvard is seeking a highly motivated, enthusiastic Bioinformatics Specialist to work with and support our research group in analyzing sequencing data to identify structural variants within the human genome using genomic population databases and aggregating phenotype and genotype datasets.
We are comprised of an interdisciplinary group of scientists, technicians, bioinformaticians, computational biologists, and postdoctoral fellows who work together in a mutually supportive and respectful environment. Ideas are freely shared, and contributions are highly valued. We are dedicated to characterizing genomic variation contributing to human disease, with a focus on the relationship between genome structure and function. The lab integrates molecular and computational genomics methods to investigate the genetic architecture of neuropsychiatric disorders and develop new technologies for translational applications in genetic diagnostics. The lab has served as a hub for novel gene and variant discovery and functional genomics modeling in common complex and rare Mendelian disorders. We are seeking a candidate to perform high-quality, large-scale computational analyses under the group leader's supervision in a timely manner. Successful candidates are expected to excel at critical thinking, be quick learners of new analytical approaches, and be able to apply or develop novel computational methods to solve complex problems. Candidates should have practical experience with programming languages, such as Java, C++, R, and/or Python. Must also have experience with computational analysis, algorithm development, and statistical analysis. Knowledge of existing bioinformatics analysis tools, methods, and databases is a significant plus. This position is hybrid, and candidates can work remotely as needed. Essential Functions -Assist in the analysis of biological data using bioinformatics tools and software. --Perform data processing, quality control, and database maintenance. -Collaborate with research teams to understand their data analysis needs. -Support the development and implementation of data analysis pipelines. -Conduct basic statistical analyses and data visualization. -Participate in the interpretation and presentation of results. Working under very general supervision, the Bioinformatics Analyst will have demonstrated independent design and innovation in one or more of the following areas of specialization: algorithm development, data analysis, quality assurance/testing, pipeline software/computing development, user interface design & report development, web-based application development, or report development. Required for All Jobs Performs other duties as assigned Complies with all policies and standards Does this position require Patient Care (indirect/direct)? No Education The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. | |