Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 129 |
Senior Manager, Clinical Operations
Cambridge, Massachusetts
Overview The Sr. Manager, Clinical Operations is accountable for the end-to-end clinical trial delivery, providing operational leadership and oversight of cross-functional deliverables and leading a cross functional trial team to build and ...
14h
| Job Type | Full Time |
Sr Manager, Statistical Programming
Cambridge, Massachusetts
The Senior Manager Statistical Programming will provide leadership and expert-level hands-on support to programmers. The senior manager may also guide the professional development of statistical programmers within the company.The position r...
14h
| Job Type | Full Time |
Associate Scientist II, Oligonucleotide Synthesis
Cambridge, Massachusetts
Overview We are looking for a talented and highly motivated Associate Scientist II to join our RNA synthesis group and support our mission to deliver the next generation of RNAi-based medicines. The successful candidate will contribute to t...
20h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: We are seeking a Head of Biocatalysis to lead the discovery, engineering, development, and implementation of enzyme-enabled technologies across our portfolio. This individual will define the company's biocatalysis strategy, build ...
20h
| Job Type | Full Time |
Senior Manager, CRM & Lifecycle Marketing
Cambridge, Massachusetts
Overview The Senior Manager, CRM & Lifecycle Marketing is responsible for executing and optimizing lifecycle marketing programs across owned channels (email, SMS, direct mail), with a focus on building and delivering scalable, data-driven c...
1d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Specialist, Quality Operations QA is an experienced senior level position within Quality Operations. This position will provide on-site operational support from Monday - Friday during the hours of 8 AM - 4 PM at Alnylam's Norto...
1d
| Job Type | Full Time |
Scientist, Target Discovery & Validation
Cambridge, Massachusetts
Overview The Target Discovery and Validation group at Alnylam is seeking a motivated and knowledgeable Scientist in the early target space. This is an exciting time at Alnylam, with our liver platform well validated and rapidly expanding to...
1d
| Job Type | Full Time |
Scientist, Oligonucleotide Drug Substance
Cambridge, Massachusetts
Overview: The Scientist, Process Sciences will be responsible for development, characterization and scale-up of speciality starting materials used in the Oligo DS manufacture processes. The successful candidate will work closely with intern...
1d
| Job Type | Full Time |
Associate Director, Case Management Vendor Oversight
Cambridge, Massachusetts
Overview The Associate Director, Case Management Vendor Oversight (CMVO), Global Safety Operations is responsible for implementing processes and procedures to support the oversight of ICSR processing activities as well as maintaining regula...
2d
| Job Type | Full Time |
Executive Director, Employment Counsel
Cambridge, Massachusetts
Overview: Alnylam is seeking an Employment Counsel to provide strategic leadership for the Company's global employment law function. Reporting to the SVP, General Counsel, Corporate and Governance, this role will evolve, lead and execute Al...
2d
| Job Type | Full Time |