Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 96 |
Vice President, Head of Pharmacovigilance Operations, Innovation & Analytics
Philadelphia, Pennsylvania
Overview The Vice President, Head of Pharmacovigilance Operations, Innovation & Analytics SRM is a critical executive-level role responsible for defining, governing, and scaling the operating model that enables Alnylam's Safety & Risk Manag...
23h
| Job Type | Full Time |
Vice President, Head of Pharmacovigilance Operations, Innovation & Analytics
Cambridge, Massachusetts
Overview The Vice President, Head of Pharmacovigilance Operations, Innovation & Analytics SRM is a critical executive-level role responsible for defining, governing, and scaling the operating model that enables Alnylam's Safety & Risk Manag...
23h
| Job Type | Full Time |
Senior Manager, Preclinical Study Management
Cambridge, Massachusetts
Overview The candidate will be responsible for overseeing externally contracted in vivo and in vitro studies supporting both research and early development programs. This role will collaborate closely with internal research and development ...
23h
| Job Type | Full Time |
Medical Science Liaison-(Los Angeles/San Diego)
Cambridge, Massachusetts
Overview: We are seeking an experienced Medical Science Liaison (MSL) to join the TTR team and support Alnylam's commitment to advancing the science and care of patients with transthyretin (TTR) amyloidosis. Patients often experience prolon...
23h
| Job Type | Full Time |
Director, Pharmacovigilance & Safety Technology
Cambridge, Massachusetts
Overview Alnylam is the world's leading RNA interference (RNAi) company, dedicated to transforming patients' lives through innovative medicines. As the global development and commercial portfolio expands, Safety & Risk Management requires s...
23h
| Job Type | Full Time |
Submit Your Resume for Future Opportunities at Alnylam's Norton Manufacturing Site
Norton, Massachusetts
We're growing in Norton, MA! A major expansion is underway at our Norton, MA manufacturing site, and we're planning ahead for significant growth across multiple teams as we continue to expand our manufacturing capabilities and advance our p...
1d
| Job Type | Full Time |
Sr Director, IT - Ethics, Compliance & Legal Technology
Cambridge, Massachusetts
Overview As Senior Director, IT- Ethics, Compliance & Legal Technology, you will lead the technology-enabled transformation of the capabilities that support Alnylam's Legal and Ethics & Compliance organizations. You will translate functiona...
4d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The Director, Product Development (Process Sciences) will lead process development, optimization, scale-up, process characterization and pre-validation for all RNAi drug products at Alnylam. The successful candidate will work clos...
4d
| Job Type | Full Time |
Director, Ethics and Compliance, AI & Technology Governance
Cambridge, Massachusetts
Overview Alnylam is seeking an experienced Artificial Intelligence (AI) and emerging technology governance leader to establish and mature the Company's enterprise AI governance. Reporting to the Head of Privacy, AI and Data Governance, Trai...
4d
| Job Type | Full Time |
Business Account Executive, TTR - Orlando, FL
Cambridge, Massachusetts
Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. Patients with TTR amyloidosis often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to ...
4d
| Job Type | Full Time |