Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 105 |
Senior Director, Clinical Pathology
Cambridge, Massachusetts
Summary of Key Responsibilities: Clinical pathology assessment of preclinical results for platform and program support Review non-GLP and GLP study clinical pathology data Clearly interpret and report findings and position significance to p...
2h
| Job Type | Full Time |
Associate Scientist II, Delivery Biology
Cambridge, Massachusetts
Overview We are seeking a highly motivated Associate Scientist II in Delivery Biology to support our efforts focused on improving the cellular delivery of nucleic acid-based therapeutics. The successful candidate will play a key part in gen...
2h
| Job Type | Full Time |
Associate Director, Site and Monitoring Health
Cambridge, Massachusetts
Responsibilities: The Associate Director, Site and Monitoring Health Team Lead will provide strong leadership, GCP expertise and clinical operations experience to drive the monitoring strategy for trials in their assigned program(s). They a...
2h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Senior Network Engineer provides technical support for Alnylam's global network infrastructure across corporate offices, R&D labs, manufacturing/OT environments, and international sites. This role leads major network initiative...
11h
| Job Type | Full Time |
Cambridge, Massachusetts
ThePrincipal Medical Writer(equivalent to Associate Director) represents medical writing on multi-disciplinary teams, collaborates on the development of clinical documents in accordance with all applicable regulations, Good Clinical Practic...
1d
| Job Type | Full Time |
Director, Enterprise Learning & Development
Cambridge, Massachusetts
Overview Alnylam is seeking a Director of Enterprise Learning & Development to shape the future of learning at scale. This role will lead the evolution of how professional skills and capabilities are developed across the organization, ensur...
1d
| Job Type | Full Time |
Business Account Executive, TTR - Trenton, NJ
Cambridge, Massachusetts
Overview: We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. Patients with TTR amyloidosis often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to...
2d
| Job Type | Full Time |
Business Account Executive, TTR - Western MA (Springfield, MA, Worcester, MA)
Cambridge, Massachusetts
Overview: We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. Patients with TTR amyloidosis often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to...
2d
| Job Type | Full Time |
Associate Director, Medical Education Marketing, US Congress and TLL Asset Lead
Cambridge, Massachusetts
Overview: The Associate Director, Medical Education Marketing, US Congress and TLL Asset Lead will lead national strategy and execution for Alnylam's US congress presence and the Thought Leader Liaison (TLL) marketing and insights. This ind...
2d
| Job Type | Full Time |
Director, Regulatory and Safety Sciences Technology
Cambridge, Massachusetts
Overview Alnylam is the world's leading RNA interference (RNAi) company, dedicated to transforming the lives of patients through innovative medicines. As Alnylam continues to expand its global development and regulatory footprint, Regulator...
3d
| Job Type | Full Time |